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Bicycle 5-5 Library

In collaboration with Pr. Gérald GUILLAUMET (University of Orleans), we  developed methods to functionise 3 series of Bicycle 5-5 containing 3 nitrogens. This leads to new and original libraries.

  • Série 1H-imidazo[1,2- b]pyrazole
    We developed methods to functionise this type of bicycle to provide di-, tri- or tetrasubstituted compounds.
  • Série Imidazo[1,2- a]imidazolin-2-one
    Two positions can be fonctionalised by alkyl or (hetero)aryl groups.
  • Série Imidazo[1,2- a]imidazole
    For this series, 3 positions can be fonctionalised by aryl or heteroaryls groups.