This tool was developed at Greenpharma. It consists in a docking software to predict interaction energies of a ligand with a protein and a database of 10 000 protein structures with annotated biological properties – eg antibacterial, anti-inflammatory, aging… The goal of this unique software is to allow in silico biological profiling. It provides predictions on the potential selectivity and/or the synergy that molecules may have on a set of protein targets – hence the name of Selnergy.
Selnergy has proven its usefulness in finding cosmetic applications for natural compounds, hence extracts containing these compounds – see our studies of meranzin and ε-viniferin. It has also been used in drug repositioning with success – see our investigation with Tofisopam.
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